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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '213c8b4c97e32305f657f20b4e671d5e81e8e25a0e605b6c3c63716f3709f9dd' 
  AND token = 'WrNuBkg1+yHZ7DmIUzp33XaL9OBtAAqWiwnQEXhZ9uI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}