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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8872e61283c945a859c8a7e0e8db219921ca87ac2ca558b795fd109a2eb0e4c6' 
  AND token = 'Q3ArITIbU7UwXzwRJwWwVlU69yCrzU6Tc5MNmVLLbHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}