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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446b54db27990ac080277cea76c12a2776965d87a7a46e1e1a1a2be7935b3bea' 
  AND token = 'vtQmhO+DTH5x32lvtridJgRpoGEqtU4Pk2IQ5v+jPWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}