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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ec4de1bece1639d47d65985f84bb2ee2eebca2fd1e1db66f0fd940bd90894b' 
  AND token = 'Zs+jWf+ek6PnLUyLjFO8FWscvPLnCjIuZUJCibMYl2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}