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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d47009d1afc73006d5ac65c872083db9d11bddbced8538683dd6bc8afdeac7b' 
  AND token = 'CxevrSTOVotWAXLjRz3gkb+KkKQhhPCrsMz3UCeS0J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}