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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd640a81be1d36d5ba4fe5ca176ec9426681d12b8798057da2b8d42e33c959c9' 
  AND token = '3OuBYltWSRt8DAi+Cnl/XkOHbfVoA54ZBmAyYJm7RA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}