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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8baede505cd44d28af92a6ce1e441bb5a352829d3e338dd4f2990e64c4eecb5' 
  AND token = 'rH4j2kk+h9N2M6f2xt4+6qJLAOwdtcu14H/ZtDVFbAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}