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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efbc1290a830e4efea9057590ab9c94b75fc82d00670f8bdc62d4bbea641dcf' 
  AND token = 'rSK6S8dKaGPTbuOZr2Vb5hgDjaSnLDZV5EYqSehEBzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}