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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8f15148bc352df744970e2f7f7f02f13ee2f1bb27f10e92a2bd1732762535e1' 
  AND token = 'LJ7WL8erqCAkQBnJ4pxmt8cR+cFcFZEzoUEaB/+V/DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}