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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ccc5e6608391fb891516a827a7a9285a1a9624a37fe636db12ef2c0a9c6f064' 
  AND token = 'rfEwOoV+zRTiNuwZFF3T9/CfaLdQXlIkeE6lqTXWbZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}