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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81a062b25ad0bed93035f50c043595d73e9d84bfbc3c0f509f2905db3ca2ff3' 
  AND token = 'Q+n6KAR5eyy1ToV91+CAMvczUC8ULYFgfDwDZm7sS5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}