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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0260e7f52927433770bdd63b15ef7046cc1e143c38c859f1720f69e70b6f7cd' 
  AND token = 'NtpldyhWEMUw68SSNPvRutYGhPbF6IlcEQ4A03KsuE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}