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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7d111314163fb112dffc5f0e3904c48cd976845cf14e951aff617e7c0b0b1f1' 
  AND token = '1bPcwC1mn/fEIS8ZcxWT9G75h9s4Ziq6xVsqhZcsbyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}