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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cac115cbe3158bba1f200705678cdd7712b07bf9e378f909008203a43b0b2cf' 
  AND token = 'JXRPL6pdLTRp9lJxTjl8aJc3R2xPVQgtUQBR79aSv90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}