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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a6442dcef94c6bdf7fb0956dde3c0815e57d374997bb6b8d0ac2ea90d4938b' 
  AND token = 'urNiIbCbd7bm+VJd0XH/2/TnnVU7DH/I0PiDI6G7IRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}