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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b51463d2f08b12e7c82d2f8b6dff8f66bfb2f40f0cfff0226edacc9d9efff7a' 
  AND token = '1gRTRv9bU3S8VoIbTGOTZ+aFXj8pCimxRMHF/4OSQSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}