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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8f9d9e5e5eab8f7e566446f4298a0faff9e83d77ef5450f02cfa47a0818fd1' 
  AND token = 't4P0V/r/K3GLP4hMB1tGTX5qsZgkw39VSCI5oFTRw+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}