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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a463dda8ca56a401d8e63d036feaff3010a65a143c0edbfdd22413763cd22b' 
  AND token = 'uvEiMsqBBcNXdJiq2pXBM5VpGqhNxKstiYlA5su8/UU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}