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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0207717c8429a4808e5405cbd469645804234946cd871fadfeb047f65f0db5f' 
  AND token = 'GWQpI/L5M4zrooj39e1CesbSTT9Khz4LYuzvuLYZ1AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}