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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22937e380e2a1a07ad69bdd691ebe4ee0f3be5f9cbf8b514279d918cc86833e' 
  AND token = '66r34FJGahx+0ofiM1H7vqVV9FIPTBWPrixb7TakAVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}