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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '285a88ad8731b2be388c10c68b6d41eaa038f4a9dfc5ed01ac9e784081186963' 
  AND token = 'ydldBtzrhjKb7GaJVGyAZFmzjSOk+5m5jIuw2c6knFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}