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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219f2123ef9e8aa05b44f9e437145a117b7d40960ebed7c0539425dee53849a4' 
  AND token = 's3rz0jrGqO/2xpTPMoigI+90A9miCOvAQC6ks/XeDmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}