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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280ef44cf0ceb3bd691f8796d1a0c325f6c811a3c78d21c0e8795edd6de36ba4' 
  AND token = '+XgQd5O9fNhj4O+roy5yTwNAkozuORz2Oz7xN41oeds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}