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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c5b1c8b8008b56a99e0859c4f68304efb2530169d04e60c19e270e7314b918c' 
  AND token = 'MZQThhC0uAB+KDl0mTQl6s5UeWbMfJZ7QSwWQUstFIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}