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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cafa8d864a5aa38537c50e5e8f05bcc1011b9e24f598d1606a4f68bee598573d' 
  AND token = '3UeRLb9VNMZH+HewrPR7UOPnMSzHpLLTHbSBlEBVT4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}