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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122d593cbf6b079250bb27a0ea5f5af5bfd1b7e5cb568ff5077cd98faf48a499' 
  AND token = 'UfBnXY3qfxtBvvCMun26brYHOGG6W4bfbzShvn68ZZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}