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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb845b70e9fe84eca201e3c42b6a302db328b804e777feefdf42aff9947e7906' 
  AND token = 'DGGClsjMi+GwJwUf4bYS1bq5h4d7cKvDcfWF+TTg94g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}