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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffddda1afd2a01bf1c7dc5a0acecca7acddd7c6a7cecf7c9fc630d300b071d8' 
  AND token = '3+tnmL16bZv0tSk//Sh4QP1QLhTtb3ngJ7/Gl7qTqNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}