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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab21142a61f9faabd4db80037a0e3179e24baf86c2a0d3da583b6dcf949b99f2' 
  AND token = 'iCk6QkP3LhHXlgEdurfEpPRPjp/ygrHCrMXB8D9hxyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}