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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f12947215967663dbca1b63b4ae6dd075f7c9b67ca711058653babf1758123e' 
  AND token = 'WHhvnDz8XAwZ+8bMiXe4zOyZTAxVSAXcPbn2PvBeEQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}