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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8da4d95b4714dfd8729b28a34bf559b6161afd1b391fca0ee87630acda3527' 
  AND token = 'Uqzy3M2C9w6xdAeGAJ+pTnIej2iAskeG1ZW9gKPe/KA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}