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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df782eb736c0fe8ce6bc9871528648bb5d359f09d4c7bf2789f860d9d2d40526' 
  AND token = 'amS6c8IQEcjgrAlKMQiJKvLGQYiA9DeuojjAjGKOWlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}