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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97eab9de11483ea0c23cf48e0fbdb25f22d2a2c110c29dd3c2f437eece23feb5' 
  AND token = 'JOjOstd/gpb6q3QG2DryggQ78xHGvD+ndE12R/MVHN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}