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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a854a5709f3fa9458566ca30e3840fc14b86e5bc5c5cfd195ddc09f203acc9a2' 
  AND token = '8Rwjl0wyoMeW36xRBL4wICjaWGI2FkIJWgaQS/6+rx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}