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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cff1b67154a527579fe429fe8271ba76f75f27e8cd8e48d8d8ba38a0d851df' 
  AND token = 'NMcwhUvS6icLZUvNCauFUTdh0jf3lZPDi92sU+sggas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}