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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e7f9cf36d28e634801be2f5fa6c36abaa68c08b06fef61008cf09277a52934' 
  AND token = 'nSVzXJiDslq9G9kfeJP9gn/Ry+qEfbe+Pt4C45wvzEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}