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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b1ed0fc9f98c0532b9fc92551b4a538269e4e3f4525588bbf3d9b8be9169c6' 
  AND token = 'GrnKtUNB5P/vv5lKX/9/R1P5xV4cWKU12ODjJcdjWks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}