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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f09dbef6be3f7dc018a26bc7dc65933cdc701526aecd0fbc5e30764575a3f76' 
  AND token = 'S7VTnJsy5+rERuoNWDLeeoXZ4IcXVkymXlT6Ds6uKFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}