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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a61c15103178dfe25fb2a9ff9c9f40a4f477087bb2e9573ff43e7f52a03eea6' 
  AND token = 'uxAsFTKCODgzKlTSROpbVX0Cf/CYtDuc4xtrX/Y4LOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}