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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a1ce92a18badb2050125ecad6683f9770ee7ecc57496c76b4429ab07264edf6' 
  AND token = 'cUGE331Dq1cOCO0hocyHqn+7UwbDONTIf9SALNX2Ic4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}