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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4545fc0d1ecd07a7e44f5031d4462c0f55725dfcc4438e3cb852f199ca33a601' 
  AND token = 'zOc5egfCOLdSs9RJTT4RrLlMK7iVdO901BhiXNMpxZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}