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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5a5539be8ca244af960084e2a18c2bd1645121016be4656d14a9fa358e608a' 
  AND token = '5dvKkaPR0prjXfAQTrjjJhpSmMKC2JWEBIPqxo51PAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}