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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b10e51fc85acebb03d87d3f8511774a6d5115abb90b2439219b837153f7c266' 
  AND token = 'K0sUU9FKiBhlRtUPIZSnl8wRq8LRRWebc2rE5Liaus8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}