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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2131352a7a258ac71359af8e6d12fe65a5ead3ac713655ccb4fa098d6760fe20' 
  AND token = 'Kd975Tu3zAAZFQ6SrfbLzCXrBE0bkRYpG3ud1fhY9dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}