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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bcd459c7fa5922f3d1c8bd5f4edc32db084e9f2b5d0f46163c2339d777a386' 
  AND token = 'iIo3jpJ66X3pNDoUgod+IcMu9j3gAybRxx9dJp5A7Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}