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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a78718c4343a7497001abecfbbee69dc151c7cef745aa49c4665bdf924b0c60' 
  AND token = 'McMq9l4LKaJZAqwRafX+gV8YuFuxC6XUl+f3CFtr1aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}