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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57373183f7b7fdb410e17fe6f544e26b3067864cd2561b4953e023d8b3e8a851' 
  AND token = 'Xi6SVDUoMZYsykxYIK8DzHjsm4B3fXDGt6WeNjRTOiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}