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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6daed6157de341233b8b921d4e8fc870e6e375e7109981087a9d8ce7afeebd56' 
  AND token = '6/eDDjmrAG7rJZDCkjDhXSB0W+83ffjOutl4P8SlVEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}