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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0684dccc6acd16726f8e7758716eeff50971bfa88e43c889d0bec333df9c0330' 
  AND token = 'KCqIWCmBfe1yjzZZQ3CUVRt6L5f21QAfky0UL4jXpOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}