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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4272031dc4d2ad99b00ec41f7205b8fc645fb13d3c634d257b63ea6caf41614f' 
  AND token = 'p551ZmeZpbomGNf7K34YLdUxFuFQgDD971su1MIBuFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}